Police were dispatched near Fleet Street and Dewdney Avenue East on Saturday at 11:29 p.m., after reports of a vehicle being shot at.
Two victims in their car said they were followed by four people in another vehicle.
After driving west on Victoria Avenue, the victims said four to five rounds were shot at their car.
The suspects’ vehicle is described as a white Chevrolet Malibu with rust around its wheel wells.
The driver of the suspect vehicle is described as an Indigenous male between 30 and 40 years of age with a buzz cut. The three passengers in that vehicle are described as heavy-set Indigenous females with straight dark hair.
Anyone with information is asked to contact the Regina Police Service at 306-777-6500 or Crime Stoppers at 1-800-222-8477.