The bank in Vibank was the scene of a robbery at noon on Tuesday.
Police say a man wearing a motorcycle helmet, gloves and a black leather jacket walked in and demanded cash.
He did not have a weapon and no one was hurt, but he did get away on foot with an undisclosed amount of cash.
Vibank is about 50 kilometres southeast of Regina on Highway 48.
Anyone with information is asked to call Indian Head RCMP or Crime Stoppers at 1-800-222-8477.